The incumbent of this position is the Deputy Chief of the Center for Cellular Engineering (CCE) and serves as an alter ego to the Chief and fully shares with the direction of all phases of the Center's program, work and staff. The CCE, located in the Department of Transfusion Medicine (DTM), is responsible for the manufacturing of cell and gene therapies for phase I and II clinical trials; processes hematopoietic stem cell grafts for transplantation at the NIH Clinical Center; develops new cell therapies; performs in-process and lot release testing of cell and gene therapies; develops new assays to test cell and gene therapies; prepares chemistry, manufacturing, and controls (CMC) documents for investigational new drugs (IND) and summary data for annual reports to the Food and Drug Administration (FDA); teaches DTM staff and visiting fellows about cell and gene therapy concepts and techniques; and provides transfusion medicine and cell therapy medical consultant services.
The ideal candidate should possess a doctoral-level degree from an accredited college or university in an academic field related to the health sciences or allied sciences appropriate to the work of the position.
As the Deputy Chief, the incumbent fully assists the Chief in carrying out the following duties and responsibilities for this dynamic and expanding organization:
- Setting the strategic direction for the CCE and determining the necessary goals, objectives and initiatives to achieve the strategic direction and developing plans to implement these;
- Developing and implementing more efficient and streamlined methods and procedures to accomplish the goals and objectives of the CCE;
- Assisting the Chief with the GMP cell processing facilities design, function, and maintenance;
- Overseeing quality improvement related activities to promote safe and efficient CCE services;
- Developing, and implementing budget strategies to support organizational expectations;
- Managing the administrative matters of the CCE including contracting, procurement, space, property management, safety, and inventory control;
- Collaborating with other Clinical Center and NIH leadership to identify the emerging needs and state of the art developments in the field of cell engineering;
- Actively supporting a culture of quality and safety across all CCE processes; and
- Representing the CCE and the Clinical Center to other agencies, accrediting organizations, and other related external organizations, etc.
Successful completion of a full 4-year course of study in an accredited college or university, leading to a bachelor's or higher degree, with major study in an academic field related to the health sciences or allied sciences appropriate to the work of the position.
Additional Qualifications: You must demonstrate in your resume at least one (1) year of qualifying experience equivalent to at least the GS-14 level in the Federal Government. Experience refers to paid and unpaid experience, including volunteer work done through National Service programs (e.g., Peace Corps, AmeriCorps) and other organizations (e.g., professional; philanthropic; religious; spiritual; community; social). Volunteer work helps build critical competencies, knowledge, and skills and can provide valuable training and experience that translates directly to paid employment. You will receive credit for all qualifying experience, including volunteer experience. Examples of qualifying experience include: directing or leading a cell therapy, gene therapy or regenerative medicine manufacturing group or center; directing or leading a cell therapy, gene therapy or regenerative medicine product development group; and directing or leading a biomedical science research center or large research group.
Internal Number: NIH-CC-DE-19-10405361
About Clinical Center, Department of Transfusion Medicine, Center for Cellular Engineering
At the NIH Clinical Center, clinical research participants—more than 500,000 since the hospital opened in 1953—are active partners in medical discovery, a partnership that has resulted in a long list of medical milestones, including development of chemotherapy for cancer; the first use of an immunotoxin to treat a malignancy (hairy cell leukemia); identification of the genes that cause kidney cancer, leading to the development of six new, targeted treatments for advanced kidney cancer; the demonstration that lithium helps depression; the first gene therapy; the first treatment of AIDS (with AZT); and the development of tests to detect AIDS/HIV and hepatitis viruses in blood, which led to a safer blood supply. Patients come from all 50 states and from around the world.