We invite applications from outstanding candidates to direct the Trans-NIH RNAi Facility located within the intramural division of the National Center for Advancing Translational Sciences (NCATS). The intramural division of NCATS studies translation of basic discoveries into tangible improvements to human health at a systems level as a scientific and operational problem. The scientists within the division come from a broad range of scientific disciplines – including, among others, therapeutic discovery, preclinical development, toxicology, biomarkers and clinical application – to reduce, remove, or bypass significant bottlenecks across the entire continuum of translation and to train the future translational science workforce.
The Leader will direct the laboratory operation of the Trans-NIH RNAi Facility, comprised of several biological scientists with further informatics, automation, compound management, and project management support. The mission of the Facility is to collaborate with NIH intramural investigators to conduct genome-wide RNAi screening projects, including assay development, screening, and validation, in order to understand functional biology and accelerate target discovery and validation. In addition, the Leader will be expected to develop methods that advance the science of RNAi screening, and to perform education and outreach to increase awareness of the RNAi program tools and methods. The Leader will also be expected to pursue new technologies for exploring gene function, including but not limited to CRISPR/Cas9 and related gene-editing approaches, as well as the interrogation of biological systems with annotated sets of perturbagens, to advance the scientific breadth of the Facility.
Qualifications: Applicants must hold a doctoral degree (MD, PhD or equivalent) in a relevant field and be a recognized expert and accomplished leader in the field. S/he must have a strong track record in the development of functional genomic and high-throughput cell-based assay systems, commitment to diversity and inclusion in the workplace, and track record of management of a complex biomedical research operation. Experience in monitoring operations in matters related to personnel, budget, contracts, interagency agreements, and research grant writing and monitoring, including tracking requests for supplements, extensions, and other related administrative issues is required. Experience in the screening of druggable compound libraries, and validation of gene expression profiling utilizing quantitative real-time PCR (qPCR), RNA sequencing, and related technologies is desirable. The ideal candidate will be highly innovative, interactive, and collaborative, and will serve as a spokesperson for the Facility at NIH and at national and international fora.
Salary and Benefits: The current salary range is commensurate with experience and accomplishments; a full Civil Service package of benefits (including retirement, health, life and long term care insurance, Thrift Savings Plan participation, etc.) is available.
To Apply: Please submit a cover letter describing your interest in the position including a career synopsis including commitment to diversity and inclusion in the workplace (1-3 pages); statement of research interests (1-2 pages); a current curriculum vitae and complete bibliography; and the names and contact information of three references to NCATSRnairecruitment@mail.nih.gov
Application packages will only be accepted electronically. The position will remain open until filled. All information provided by candidates will remain confidential and will not be released outside the NCATS search process without a signed release from candidates. The NIH encourages the application and nomination of qualified women, minorities and individuals with disabilities. DHHS and NIH are equal opportunity employers. The NIH is dedicated to building a diverse community in its training and employment programs.
About National Institutes of Health
The National Institutes of Health (NIH), a part of the U.S. Department of Health and Human Services, is the nation's medical research agency making important discoveries that improve health and save lives. NIH is the largest source of funding for medical research in the world, creating hundreds of thousands of high-quality jobs by funding thousands of scientists in universities and research institutions in every state across America and around the globe. NIH is made up of 27 Institutes and Centers, each with a specific research agenda, often focusing on particular diseases or body systems. The NIH main campus is located in Bethesda, MD