Summary: Responsible for performing custom organic synthesis to make compounds, solve synthetic problems, and related functions by performing the following duties.
Duties and Responsibilities include the following. Other duties may be assigned.
Plans and executes various chemistry reactions for compound synthesis (run, work-up and purify reactions)
Devises alternative synthetic routes
Skilled in purification techniques, including chromatography, crystallization or distillation
Skilled in standard and reverse phase chromatography
Provides weekly written updates and final synthesis reports to supervisor(s)
Search for alternative scientific routes utilizing journals and online chemistry software (Scifinder, Reaxys and publically-accessible databases)
Loads compounds into the LCMS & NMR; interprets data. Submits compounds to analytical chemist for full composition and purity analysis
Maintains a chemistry synthesis notebook(s) and raw material lists
Maintain a clean and safe laboratory work area
Submit orders for chemicals to purchasing
Oversee specialized equipment (e., microwave, Prep HPLC) as delegated
Participate in project specific haz op reviews
Supports facility group in removing/quenching outdated chemicals
Mentors/trains chemistry employees (MS Chemists, BS Chemists and undergraduate interns)
Provide oral updates to customers as requested
Performs other related duties as assigned.
To perform this job successfully, an individual must be able to perform each essential duty satisfactorily and efficiently. The requirements listed below are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Ph.D. in Chemistry required.
Ability to critically read, analyze, and interpret scientific information from diverse sources (periodicals, professional journals, technical procedures, patents or government documents). Write scientifically rigorous reports and synthesis procedures in order to enable other researchers. Effective presentation of information and respond to questions from managers, co-workers and external collaborators
Ability to work with mathematical concepts such as probability and statistical inference, and fundamentals of plane and solid geometry and trigonometry. Ability to apply concepts such as fractions, percentages, ratios, and proportions to practical situations.
Ability to define problems, collect data, establish facts, and draw valid conclusions. Interpretation of technical information from disparate information sources, and deal with several abstract and concrete variables. Proficient knowledge in selection of reagents and attendant reaction mechanisms, with prioritization of appropriate reaction conditions, in order to maximize probability of success.
To perform this job successfully, an individual should have extensive knowledge of Microsoft Word, Microsoft Excel, PowerPoint, ChemDraw, Reaxys, and Scifinder.
Must be able to use the following equipment on as-needed basis:
Multi-nuclei 300 MHz NMRs
Buchi Melting Point B-545
Biotage and Analogix Chromatography Systems
Karl Fischer Titration Test
The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
The noise level in the work environment is usually moderate to loud.
The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
The employee must occasionally lift and/or move up to 40 pounds. While performing the duties of this job, the employee is regularly required to sit; use hands and talk or hear. The employee is frequently required to walk. The employee is occasionally required to stand and stoop, kneel, crouch, or crawl.
About Adesis, Inc.
Adesis, Inc. is a contract research organization (CRO) supporting the pharmaceutical and biopharmaceutical industry, biomaterials, and catalysts industry. It specializes in organic and organometallic synthesis, in milligrams to multi-kilogram quantities. Adesis has a business model of providing clients with organic chemistry services in three areas: early stage research, scale up and development, and specialty manufacturing. We have been successful for over 20 years by taking a different approach than other CRO’s. Our leadership team of scientists implemented a simple approach: hire talented chemists with exceptional work ethics, integrity, versatility, and a commitment to deliver the project/material to our client.