The Department of Internal Medicine at the University of California, Davis invites applications for the position of Junior Specialist.
The Junior Specialist appointee will be involved in interdisciplinary studies focusing on questions in chronic obstructive lung disease and inflammation. These studies will involve the coordination of services and data from multiple disciplines within the health system, including but not limited to physiology, biochemistry, radiology, and clinical research.
This position will be housed in the Division of Pulmonary, Critical Care, and Sleep Medicine facilities at the Medical Center and also at the UC Davis Center for Comparative Respiratory Biology and Medicine (CCRBM). The incumbent will be involved in interdisciplinary studies to determine the role of airway inflammation in chronic obstructive pulmonary disease (COPD) and other clinical studies involving advanced lung disease. The aim of the CCRBM is to resolve the disease problems associated with the respiratory system, using a strong interdisciplinary, multidisciplinary approach which integrates basic cellular biology with animal models and clinical applications of therapeutic strategies. The Center serves as the focal point for the large and diverse research community at UC Davis whose interests focus on the respiratory system.
The Junior Specialists will participate in projects under the supervision of collaborating PIs at the UC Davis Health System and the CCRBM:
Research and Evaluation (90%):
Assists in the implementation and evaluation of research activities related to a Tobacco-Related Disease Research Program (TRDRP)-sponsored grant to study pulmonary innate lymphoid cells and airway inflammation in obstructive pulmonary disease, amongst other projects. The TRDRP research specifically aims to shed light on the question of why obstructive pulmonary disease patients are more susceptible to air pollutant-induced exacerbations than persons without chronic lung disease. To understand this, we will study 1) an immuno-protective protein called Surfactant Protein-D (SP-D), released into the airways in order to suppress inflammation caused by ozone inhalation. And, 2) a pro-inflammatory cell type called the Group 2 Innate Lymphoid Cell (ILC2), which causes inflammation in the lung after ozone (O3) exposure; and, other biomarkers of inflammation. The Jr. Specialist will assist with data and specimen collection and interpretation to test the hypothesis that impaired SP-D expression in COPD, ACOS, and asthma patients contributes to ILC2 activation and pro-neutrophilic phenotype alteration (plasticity), and thus to increased susceptibility to O3-induced exacerbations. Secondary endpoints of the study include the characterization of other biomarkers that might serve to distinguish between these conditions and an examination of the relationship between stress and inflammatory biomarker expression. The Jr. Specialist will assist with subject recruitment, data collection, specimen processing and analysis, and data analysis.
Is actively and significantly involved in publishable research activities, including reviewing journal articles and engaging in discussions on research and the interpretation of research results in concert with the research team.
Prepares research dissemination materials, including conference presentation materials and manuscripts.
Conducts literature reviews and assists with the development of study protocols and maintenance of research databases.
Professional Competence (5%):
Participate in appropriate professional/technical societies or groups and other educational and research organizations. Attend proceedings of the American Thoracic Society and American College of Chest Physicians conferences as required. Prepare and present scientific posters.
Review research proposals, journal manuscripts, and publications related to the area of expertise, specifically advanced lung disease including but not limited to COPD, asthma, and interstitial lung disease.
University and Public Service (5%):
Organizes symposia and workshops to advance the research agenda, including improving protocols and test processes.
Maintain liaison and respond to the needs of various industry organizations, state and federal agencies, and other internal groups on issues related to the research at hand.
Participate in research group Meetings for the Division of Pulmonary Medicine and the CCRBM as necessary. Collaborate with faculty to review research proposals and plan logistics of their conduct.
General responsibilities include: The position of Junior Specialist has a narrow focus in a specialized area of research in the field of nephrology clinical research and provides technical or specialized expertise (e.g., with instrumentation and research equipment, or with research methods) in the planning and execution of a research project. Junior Specialists are required to be actively and significantly involved in publishable research activities, including reviewing journal articles and engaging in discussions on research and the interpretation of research results. Junior Specialists are also expected to participate in appropriate professional/technical societies or groups and other educational and research organizations as well as review research proposals, journal manuscripts, and publications as applicable related to their research area of expertise.
The ideal candidates will have strong interpersonal, communication, and decision-making skills; as well as the ability to work well independently and as part of an interdisciplinary team. Ability to adhere to University policies and procedures.
Ability to quickly gain knowledge and understanding to efficiently and effectively learn and perform the following tasks:
Manage complex medical and clinical data and accurately enter them into Case Report Forms and/or databases.
Efficiently and effectively operate laboratory equipment and prepare laboratory samples, including hazardous biological specimens (e.g. blood, sputum, and urine).
Follow broadly defined instructions and complete experimental procedures in accordance with relevant protocols.
After adequate training, perform new technical laboratory procedures with minimal or no supervision.
Follow institutional safety guidelines when processing human specimens, using biological safety cabinets, and using protective clothing (latex gloves, laboratory coat, face mask, eye protection), and follow specific detailed instruction on the safe handling of biohazardous material.
Develop an understanding of disease processes and therapies pertaining to specific research projects (e.g. chronic obstructive pulmonary disease, asthma, and pulmonary fibrosis).
Prepare regulatory documentation for Institutional Review Boards.
Perform all work in adherence to study protocols.
Follow the regulatory requirements of the F.D.A., N.I.H., Institutional Review Board, Office of Human Research Protection, UCD research policy and procedures, and appropriate regulatory agencies.
Assist with clinical trial subject recruitment and tracking.
Plan and conduct biological sample collections from different sources, and prepare such samples for shipment as appropriate per IATA/DOT regulations.
Organize and prioritize the workload requirements.
Keep clear and accurate records and provide timely reports, and work on several projects simultaneously.
Demonstrate knowledge of safety requirements and regulations pertaining to the research, teaching and administrative functions of the department.
Aid in monitoring compliance with federal regulations governing research.
Communicate effectively with the general public, physicians, patients, and other healthcare professionals on matters pertaining to the research at hand.
Bachelor degree in biological sciences or a related field.
Excellent interpersonal, oral and written communication skills with knowledge of the correct use of medical terminology.
Use of Experience with computing equipment including Macintosh and PC operating systems; Word, Excel, Epic, and statistical analysis programs, among others.
Salary: Step II - $43,400 annually, commensurate with qualifications and experience.
Number of Positions Available: 7
TERM OF APPOINTMENT:
Short-term 2-year maximum Non-Exempt appointment, seasonal appointment based on the needs of the research project. Appointments may be made up to 100%.
For full consideration, applications should be submitted by the 'next review date' found on the application link below. However, this position will remain open until filled through June 30, 2020.
UC Davis commits to inclusion excellence by advancing equity, diversity, and inclusion in all that we do. We are an Affirmative Action/Equal Opportunity employer, and particularly encourage applications from members of historically underrepresented racial/ethnic groups, women, individuals with disabilities, veterans, LGBTQ community members, and others who demonstrate the ability to help us achieve our vision of a diverse and inclusive community. For the complete University of California nondiscrimination and affirmative action, policy see http://policy.ucop.edu/doc/4000376/NondiscrimAffirmAct. If you need accommodation due to a disability, please contact the recruiting department. Under Federal law, the University of California may employ only individuals who are legally able to work in the United States as established by providing documents as specified in the Immigration Reform and Control Act of 1986. Certain positions funded by federal contracts or sub-contracts require the selected candidate to pass an E-Verify check. More information is available http://www.uscis.gov/e-verify.
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