Berkeley Lab (LBNL) addresses the world's most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Lab's scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy's Office of Science.
The m-CAFEs SFA (Microbial Community Analysis & Functional Evaluation in Soils Scientific Focus Area) is a multi-institutional project that will develop an understanding of the interactions, localization, and dynamics of plant rhizosphere communities that is sufficient, at the molecular level (genes, proteins, metabolites), to predict responses to perturbations. m-CAFEs is a collaborative, coordinated and integrated, mission-driven program to interrogate the function of soil microbiomes with critical implications for carbon cycling and sequestration, nutrient availability and plant productivity in natural and managed ecosystems. The project targets molecular mechanisms governing carbon and nutrient transformation in soil, with a focus on microbial metabolic networks. This project seeks to develop foundational genomics tools to explore and understand molecular ecosystem biology.
Berkeley Lab's Environmental Genomics & Systems Biology Division has an opening for a Plant-fungal-microbe-soil interactions Postdoctoral Researcher. The Postdoctoral Researcher will work in the recently funded Department of Energy Science Focus Area (SFA) entitled m- CAFEs (Microbial Community Analysis & Functional Evaluation in Soils). The Postdoctoral Researcher will work on developing a high-throughput functional genomics platform for soil/rhizosphere relevant filamentous fungi and will be directed by N. Louise Glass (PMBUCB/Lawrence Berkeley National Laboratory (LBL)). Specifically, the goal of this project is to extend high-throughput functional genomics methodologies developed for single-celled organisms in the Deutschbauer laboratory (https://www.ncbi.nlm.nih.gov/pubmed/29769716) to filamentous fungi. Once developed, loss-of-function libraries will be screened via high-throughput methodologies to identify new functions, including those important for interactions with rhizosphere bacteria and plants, with a focus on Brachypodium distachyon in fabricated ecosystems (https://eco-fab.org).
What You Will Do:
Lead design and implementation of strategies for engineering filamentous fungi (e.g., RNAi, CRISPR, high throughput screening)
Perform research lab procedures efficiently and with attention to necessary quality control procedures
Maintain well-documented laboratory notebook (e-notebooks will be used)
Communicate regularly and clearly, and work with other researchers on this project in order to facilitate progress toward program goals
Work carefully but efficiently in order to meet project goals in a timely manner
Publish research results in peer-reviewed journals
Presentation of research results to internal groups and at national and international meetings
Assisting in writing project reports and updates
Additional Responsibilities as needed:
Mentoring undergraduates, graduate students and technicians associated with project
Assist with day-to-day lab maintenance
What is Required:
Ph.D in Microbiology, Molecular Biology, Biochemistry, or a closely related field
Significant laboratory and analytical experience
Computational skills for analysis of genomic, transcriptomic, biochemical data
Experience with fungal molecular biology and genome editing/mutant construction
Experience in basic molecular biology technologies: molecular cloning, transformation, western blot, heterologous expression & metabolic engineering
Ability to work effectively with scientists of different disciplinary backgrounds and serve as a communication nexus
Additional Desired Qualifications:
Working knowledge of analytical instruments to monitor microbial growth and metabolites
Experience with secondary metabolites analysis: High Performance Liquid Chromatography (HPLC), liquid Chromatograph Mass Spectrometer (LC-MS) and Gas chromatography-mass spectrometry (GC-MS) sample preparation and analysis
Laboratory experience with microcosm/microfluidic design, construction, and operation
The posting shall remain open until the position is filled.
This is a full time 2 year postdoctoral appointment with the possibility of renewal based upon satisfactory job performance, continuing availability of funds and ongoing operational needs. You must have less than 3 years paid postdoctoral experience. Salary for Postdoctoral positions depends on years of experience post-degree.
Full-time, M-F, exempt (monthly paid) from overtime pay.
This position is represented by a union for collective bargaining purposes.
Salary will be predetermined based on postdoctoral step rates.
This position may be subject to a background check. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.
Work will be primarily performed at the University of California, Berkeley, CA.
Equal Employment Opportunity: Berkeley Lab is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. Berkeley Lab is in compliance with the Pay Transparency Nondiscrimination Provision under 41 CFR 60-1.4. Click here to view the poster and supplement: "Equal Employment Opportunity is the Law."
Internal Number: 88792
About Lawrence Berkeley National Laboratory
In the world of science, Lawrence Berkeley National Laboratory (Berkeley Lab) is synonymous with excellence. Thirteen scientists associated with Berkeley Lab have won the Nobel Prize. Fifty-seven Lab scientists are members of the National Academy of Sciences (NAS), one of the highest honors for a scientist in the United States. Thirteen of our scientists have won the National Medal of Science, our nation's highest award for lifetime achievement in fields of scientific research. Eighteen of our engineers have been elected to the National Academy of Engineering, and three of our scientists have been elected into the Institute of Medicine. In addition, Berkeley Lab has trained thousands of university science and engineering students who are advancing technological innovations across the nation and around the world. Berkeley Lab is a member of the national laboratory system supported by the U.S. Department of Energy through its Office of Science. It is managed by the University of California (UC) and is charged with conducting unclassified research across a wide range of scientific disciplines. Located on a 200-acre site in the hills above the UC Berkeley campus that offers spectacular... views of the San Francisco Bay, Berkeley Lab employs approximately 4,200 scientists, engineers, support staff and students. Its budget for 2011 is $735 million, with an additional $101 million in funding from the American Recovery and Reinvestment Act, for a total of $836 million. A recent study estimates the Laboratory's overall economic impact through direct, indirect and induced spending on the nine counties that make up the San Francisco Bay Area to be nearly $700 million annually. The Lab was also responsible for creating 5,600 jobs locally and 12,000 nationally. The overall economic impact on the national economy is estimated at $1.6 billion a year. Technologies developed at Berkeley Lab have generated billions of dollars in revenues, and thousands of jobs. Savings as a result of Berkeley Lab developments in lighting and windows, and other energy-efficient technologies, have also been in the billions of dollars. Berkeley Lab was founded in 1931 by Ernest Orlando Lawrence, a UC Berkeley physicist who won the 1939 Nobel Prize in physics for his invention of the cyclotron, a circular particle accelerator that opened the door to high-energy physics. It was Lawrence's belief that scientific research is best done through teams of individuals with different fields of expertise, working together. His teamwork concept is a Berkeley Lab legacy that continues today.